File Name: nucleic acids in chemistry and biology .zip
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Last reviewed: November An acidic, chainlike biological macromolecule consisting of multiple repeated units of phosphoric acid, sugar, and purine and pyrimidine bases. Nucleic acids Fig. Each DNA strand is a long polymeric molecule consisting of many individual nucleotides linked end to end. The great size and complexity of DNAs are indicated by their molecular weights, which commonly range in the hundreds of millions. DNA is the chemical constituent of the genes of an organism; thus, it is the ultimate biochemical object of the study of genetics.
This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations roll, slide, twist, buckle, etc. This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. This handy guide ends with a complete list of resources, including relevant online databases and software. Researchers in biochemistry, as well as for advanced undergraduate and graduate students studying nucleic acid structure and function. Methods for Studying Nucleic Acid Structure.
Vester, L. Lundberg, M. Babu, S. Douthwaite, J. Biochem Soc Trans 1 February ; 32 1 : 37— DNAzymes consist of two binding arms that hybridize to a predetermined RNA sequence and a catalytic core that cleaves a phosphodiester bond held between the binding arms.
It seems that you're in Germany. We have a dedicated site for Germany. Editors: Erdmann Deceased , Volker A. This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology.
The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved.
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Nucleic acids are the biopolymers , or large biomolecules , essential to all known forms of life.Marcelo M. 17.12.2020 at 13:42
Organic synthesis services across all areas of organic chemistry.Trancatsclindows 19.12.2020 at 11:02
This volume contains 29 engrossing chapters contributed by worldwide, leading research groups in the field of chemical biology.Madison B. 23.12.2020 at 12:23
The reversible and noncovalent nature of the interactions governing the structure and binding properties of nucleic acids mean that the fields of supramolecular chemistry and nucleic acid chemistry are closely intertwined.